对羟基苯甲酸酯的合成

Synthesis of p-Hydroxybenzoate Esters with TiSiW_(12)O_(40)/TiO_2

摘要:

以固载杂多酸盐TiSiW12O40／TiO2为多相催化剂，对以乙醇、丙醇、丁醇和对羟基苯甲酸为原料合成对羟基苯甲酸酯的反应条件进行了研究。实验表明：TiSiW12O40／TiO2是合成对羟基苯甲酸酯的良好催化剂，最佳反应条件为：醇酸摩尔比为4：1，催化剂用量为反应物料总量的2％，反应时间为2h。上述条件下，对羟基苯甲酸乙酯的产率为87．5％，对羟基苯甲酸丙酯的产率为89．2％，对羟基苯甲酸丁酯的产率为91．1％。

Abstract:

P hydroxybenzoate esters were synthesis using ethanol, propanol, butanol and p hydroxybenzoic acid as reactants, and reaction conditions. It is shown that TiSiW12O40/TiO2 is an excellent catalyst for the synthesis of p hydroxybenzoate esters, and that the optimal reaction conditions are 4:1 for the molar ratio of alcohol to acid, 2.0%of total reactant mass for the catalyst, and 2 h for the reaction time. Under these conditions, yields of 87.5%, 89.2%and 91.1%can be reached for the ethyl ester, propyl ester, and butyl ester, respectively.