钛和钛合金生物活化研究现状

Research and Development on Surface Bioactivity Methods of Titanium and its Alloys

摘要:

金属钛及其合金在人体硬组织替换中具有广泛的应用。为改善其表面性能，使其具有表面生物活性，研究发展了多种生物活化方法。包括物理法、化学法和电化学法3大类。本文对钛及钛合金种植体的各种表面活化方法进行了综述。阐述了各种方法进行钛及钛合金表面活化的工艺过程及其活化机理，分别指出了各种方法的优缺点。与物理法相比，化学法具有设备和操作简单、易形成均匀涂层、结构和成分与自然骨相似等优点。对化学法，还需要进一步提高效率，提高涂层与基体之间的结合强度，并对其长期植入效果及其活化机理进行深入研究。

Abstract:

Titanium and its alloys have been applied widely in hard tissue replaceme nts of human body.Many methods were d eveloped in order to improve their surface bioactivity,including physical methods,chemical methods and electrochemi cal methods.The surface bioactivity method of titanium and its alloys are reviewed in present paper.The processing and bioactivity mechanism of every method are introduced,and the advantages and disadvantages of those methods are also presented.Co mparing with physical methods,chem ical methods have more ad-vantages as follows:simple equipme nt and process,uniform coatings on c omplex surface,and the similar stru cture and compositions of coatings to those of natural bone.For chemical methods,it is necessary t o enhance the efficiency and the bond ing strength between coatings and substrates.And the effect of lon g-term implantation and the bioactivity theory of chemical methods are d emanded to research deeply.