医用碳材料对骨组织的响应及其生物活化改性

Response of Bone Tissue to Carbon and Its Bioactive Modification

摘要:

对骨种植医用碳材料的种类、碳材料对骨组织间的响应及碳／碳复合材料表面生物活化改性研究现状进行了综述。提出了碳／碳复合材料表面生物活性改性涂层结构，认为碳／碳复合材料表面活性改性的结构应由硬质阻挡层和不降解生物活化层组成；根据目前已研究的生物活性陶瓷种类，提出了碳／碳复合材料表面生物活性涂层具体结构思路，同时展望了医用骨种植碳材料的前景。

Abstract:

Biocompatible carbon/carbon composites have good mechanical properties close to those of bone, which make them great potential as orthopedic implants in human body. Biomedical carbon types as bone implants, its response to bone tissue and bioactive modification of carbon/carbon composites were reviewed. On the basis of this summary, the structure of bioactive coating on carbon/carbon composites, which is composed of hard internal layer inhibiting the release of carbon particles and bioactive layer, is suggested, and the details are also presented correspondingly. Finally, the medical prospects of carbon/carbon composites as bone implants are shown with some problems need to be solved.