煅烧牛松质骨制备β-TCP/HAP/Ca2P2O7多孔陶瓷反应机制研究

Reaction Mechanism of Cancellous Bovine Bone Calcination for Preparing β-TCP/HAP/Ca2P2O7 Porous Bioceramic

摘要:

以牛松质骨(CBB)为原料，经过系列脱脂处理，采用低温煅烧工艺，通过调整浸泡溶液NH4H2PO4浓度及煅烧温度等工艺参数，制备出具有天然骨多孔结构的β-TCP/HAP/ Ca2P2O7多相生物陶瓷材料。利用X射线衍射分析对煅烧产物的相组成进行表征，采用FTIR、TG对反应机制进行探讨。结果表明：浸泡溶液NH4H2PO4浓度对制备的样品相组成具有重要影响，通过合理控制NH4H2PO4浸泡溶液浓度，可以获得不同相组成的多孔生物陶瓷材料。煅烧产物的相组成主要受到HAP分解的OH-量(x)和与NH4H2PO4反应的OH-的量(3m)影响，当x>3m时，煅烧产物含有β-TCP与HAP两相；当x=3m时，煅烧产物为纯相β-TCP；x<3m时，煅烧产物含有β-TCP、Ca2P2O7和HAP或β-TCP和Ca2P2O7

Abstract:

Cancellous bovine bone (CBB) as starting materials was treated by a series of degreasing and then calcined at low temperature. By adjusting the concentration of soaking solution NH4H2PO4 and the calcination temperature, β-TCP/HAP/Ca2P2O7 multiphasic bioceramic material was prepared with porous structure of natural bone. The phase composition of the calcined specimen was characterized by XRD and the reaction mechanism was discussed by FTIR and TG. Results show that the concentration of soaking solution NH4H2PO4 has a significant effect on the phase composition of the specimen. Porous bioceramic materials with different phase composition can be prepared by controlling the concentration reasonably. The phase composition was also influenced by the amount of OH- which came from HAP decomposition (x) and which reacted with NH4H2PO4 (3m). When x>3m, the product was mainly composed of HAP and β-TCP. When x<3m, the procuct may contain HAP/β-TCP/Ca2P2O7 or β-TCP/Ca2P2O7. Only as x=3m, pure β-TCP could be gained