纳米银在水相中的分散及其抑菌性能

Dispersion of Nano-Silver in Aqueous Media and Its Antibacterial Properties

摘要:

根据纳米微粒在液相中的分散受表面润湿、粒子间作用能、双电层静电作用能、空间阻力作用能等因素影响，采用十二烷基苯磺酸钠、吐温80、硅酸钠复配，通过高速剪切与超声作用得到纳米银在水相中最佳的分散条件：硅酸钠、十二烷基苯磺酸钠、吐温80浓度(质量分数)分别为0.5%, 0.5%, 2%，超声时间为1.5 h。透射电镜观测表明，纳米银在水相中分散稳定均匀。用琼脂稀释法测定最小抑菌浓度，纳米银分散液对大肠杆菌8099和金黄色葡萄球菌ATCC6538的最小抑菌浓度都为50 μg/g

Abstract:

The nanoparticles dispersed in the liquid are influenced by the factors of surface wetting, inter-particle energy, double-layer electrostatic energy, space resistance function, etc. According to this theory, the best dispersion conditions for Ag nanoparticles in aqueous media were obtained through a method of high-speed shearing and ultrasound action by use of ABS, Tween 80 and sodium silicate compound, i.e. the concentration of sodium silicate, ABS and Tween 80 is 0.5%, 0.5% and 2% (mass fraction), respectively, and the ultrasonic time is 1.5 h. TEM observation reveals that nano-silver disperser was homogeneous and stable. Through the agar dilution method, the minimum inhibitory concentration (MIC) of nano-silver dispersion for the E. coli8099 and Staphylococcus aureus ATCC6538 are both 50 μg/g