金属有机框架材料及其涂层在生物抗菌领域的应用研究进展

Research progress on the application of MOFs materials and their coatings in biological antibacterial field

摘要:

细菌耐药性问题日益严峻，对人类的健康造成了巨大威胁。面临着传统抗菌药物有效性下降的现状，开发新型抗菌材料成为了该领域的重要研究课题。金属有机框架（Metal-organic frameworks, MOFs）材料是由金属离子与有机配体组成的多孔配位聚合物，被认为是一种很有前途的抗菌材料。近年来，国内外学者已设计、制备出不同结构的MOFs及其复合材料，并将其广泛应用于各种抗菌领域。本综述以MOFs材料的作用方式和抗菌机理为出发点，分类概述了MOFs及其涂层在生物抗菌领域的应用，并对该领域的发展趋势进行了一定的展望。

Abstract:

In recent years, the problem of bacterial resistance has become increasingly serious, which poses a great threat to human health. Faced with the decline in the effectiveness of traditional antibacterial drugs, the development of a new antibacterial material has become a frontier research topic. Metal-organic frameworks (MOFs) are porous coordination polymers composed of metal ions and organic ligands, which is considered a promising antibacterial material. In recent years, researchers have prepared MOFs and their composite materials with different structures, which have been widely used in various antibacterial fields. In this paper, based on the action mode and antibacterial mechanism of MOFs materials, the application of MOFs materials and their coatings in biological antibacterial field was reviewed. Meanwhile, the development trend of this field has been forecasted.