Bioactivity of Titanium Surfaces with Micro/Nanostructure and Grafted Polypeptide

Abstract:

The mineralization ability of 4 kinds of titanium implants after chemical and bionic modification was evaluated. The 4 kinds of surface modification layers were anatase nanotubes (N), micro/nanostructure (MN), nanotubes with grafted Arg-Gly-Asp-Cys (NR), micro/nanostructure with grafted Arg-Gly-Asp-Cys (MNR). Results show that the surface mineralization deposition is hydroxylapatite. Under the same condition, the inducing mineralization ability of the samples is MNR>MN>NR>N. Combination of developing micro/nanostructure and grafting polypeptide is an effective way of surface modification for biomaterials.

Key words:titanium; surface modification; micro/nanostructure; polypeptide; mineralization