The Effect of Superficial Magnetic Films of 316L Medical Steel Stents on Endothelialization

Abstract:

The effect of superficial magnetic film on vascular endothelialization for the 316L medical stainless steel stent was investigated in this study. The in vitro endothelial response of human umbilical vein endothelium cell (HUVECs) was investigated on the superficial magnetic film 316L medical stainless steel stent vs bare-metal stent surface；as well as the re-endothelialization and platelet adhesion reaction of superficial magnetic film 316L medical stainless steel stent vs bare-metal stent were evaluated with SEM after animal models implantation for 1 month and 3 months. The consequence indicates that the superficial magnetic film 316L medical stainless steel stent can increase the adhesion and proliferation of HUVECs in vitro，and promote the regenesis of vas endothelialization after implantation in vivo, as well as speed the stent endothelialization and inhibite the platelet adhesion reaction and activation, simultaneously