Performances of Biodegradable Mg-Nd-Zn-Zr Magnesium Alloy for Cardiovascular Stent

Abstract:

Mg-3.13Nd-0.16Zn-0.41Zr (wt%, JDBM) alloy was chosen and the cell toxicity and corrosion property of the as-extruded JDBM were studied. Magnesium tube was prepared by hot extrusion processing and the microstructure of the tube was observed. The cardiovascular stent was prepared by laser cutting and electrochemical polishing processes. The surface roughness and radial expansion force were tested. The results show that JDBM magnesium alloy exhibits no cell toxicity of Endothelial cell, good corrosion resistance and corrosion mode. The radial expansion force of the prepared cardiovascular stents is over 4 times than that of the maximal vascular compression pressure of normal adult, which meets the requirement of the mechanical properties for cardiovascular stents.