Abstract:Acetone is a key biomarker for early screening and non-invasive diagnosis of diabetes. This study aimed to develop high-performance gas-sensitive materials suitable for breath acetone detection. PtAu bimetallic-modified three-dimensional ordered mesoporous SnO2 composite material (PtAu/3DOM SnO2) was prepared using a template method combined with an in-situ reduction process. The results of material characterization revealed a highly ordered mesoporous structure, a rutile crystal phase, and uniformly dispersed PtAu nanoparticles. At an operating temperature of 300 ℃, the material exhibited a high response value of 192.3 to 100 ppm acetone, a low detection limit of 77 ppb, response and recovery times of 30 s and 9 s, respectively, and demonstrated good stability and anti-interference capability over a wide humidity range. The performance enhancement is primarily attributed to the high specific surface area and rapid gas diffusion channels provided by the three-dimensional ordered mesoporous structure, as well as the synergistic catalytic and electronic sensitization effects of the PtAu nanoparticles. Together, these factors promote the adsorption, activation, and surface reaction kinetics of acetone, showing significant application potential in diabetes breath detection. .